Biology and Applications of the CRISPR/Cas System

Tools for efficient and accurate genome editing have evolved significantly over the past ten years. The CRISPR/Cas system is currently used as both a research and therapeutic tool in the fields of genetic disorders and oncology. This course is designed to provide a broad overview of the biology and applications of the revolutionary CRISPR/Cas system, with a detailed exploration of several areas using different genetic disorders as examples. Additionally, you will learn the ethical considerations for regulating human genome engineering.

The basic biology of the CRISPR/Cas9 system
High-throughput screening using CRISPR/Cas9
Use of CRISPR applications for epigenetic modifications and transcriptional regulation
Disease modeling with CRISPR and therapeutic applications of gene editing with CRISPR
Ethical considerations of the use of CRISPR/Cas9