How do we go about understanding and describing the lives of persons? How can we empathetically depict a life that respects how people actually behave, how people come to be the way they are, and how people change? While acting more or less cognizantly and intentionally, engaged in varied roles in multiple and complex communities, people encounter and construct their worlds. Working from a theory-neutral descriptive perspective designed for comparative theoretical approaches, we employ conceptual tools that facilitate an examination of the nuanced commonalities, differences, and significant through-lines in selected adults, and then apply these concepts in constructing a psychological biography or autobiography.